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In PKA catalytic subunit , R165 and D166 in the [HY]-[RY]-D-[LI]-K-P-[ED]-N motif (aka RD motif) and the D184, F185, and G186 residues (aka DFG motif) (Fig 4A) are critical for its kinase activity (Hanks & Hunter, 1995)

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221, S40S48

GH inhibition of lipogenesis and stimulation of lipolysis in sheep adipose tissue: involvement of protein serine phosphorylation and dephosphorylation and phospholipase C J Endocrinol 1996 150 : 129140