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found that QUE enhanced the sensitivity of HCT116 and SW480 cells to 5-FU by inducing autophagy and up-regulating the expression of Drp-1, resulting in mitochondrial fragmentation (32)

8:e1002471

A Key Role of the Mitochondrial Citrate Carrier (SLC25A1) in Tnfalpha- and Ifngamma-Triggered Inflammation

In terms of the presence of HE causing mental damage and impairing the patients state of consciousness, low-intensity neurological and psychiatric damage is observed, along with damage to working memory and attention, psychomotor agitation, visuospatial changes, and electroencephalographic changes

(Reference Sharma, Rawal and Mathew19) The usage of natural antioxidants as dietary supplements is on the rise as preventive and therapeutic strategies for various major health issues (Reference Saboori, Koohdani, Nematipour, Yousefi Rad, Saboor-Yaraghi, Javanbakht, Eshraghian, Ramezani and Djalali20,Reference Li, Tan, Wang, Zhang, Lao and Wong21) , and many studies have focused on them

Unfortunately, Obstructive Sleep Apnoea (OSA) may occur with TRT and is characterized by intermittent hypoxia and poor sleep 25