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Patients treated with TE were matched to patients not treated with TE based on propensity score using nearest neighbour method with +/-0.5 caliper

mTORC1 activation phosphorylates S6K1 and 4E-BP1, which directly promotes ribosomal biogenesis and protein translation initiation

TCR and chains were codon optimized and synthesized into bicistronic expression cassettes using engineered cysteine residues in the TCR constant domains, using F2A ribosomal skip sites and furin cleavage sites 52

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These aldehydes subsequently form exocyclic DNA adducts, inducing genome instability [125]

Clinical-Strength 2% GHK-Cu Twice the Standard Dose