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2013;8:e67145

10.1093/annonc/mdv388 Ann

Synaptic proteins and receptors defects in autism spectrum disorders

The cells were resuspended in lysis buffer (50 mM Tris-HCl pH 8.0, 500 mM NaCl, 10 mM -mercaptoethanol, 0.5 mM AeBSF, 10 L DNase, 1x Complete protease inhibitor tablet [Roche])

154,155 Imatinib targets PDGFR, BCR-ABL and c-KIT, making it one of several multi-targeting RTK inhibitors on the market, and is the gold-standard for treating CML and gastrointestinal stromal tumours (GISTs)