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For estimation purposes, similar to the assumptions previously used for the STEMI and Excessive Radiation Dose or Inadequate Image Quality for Diagnostic CT in Adults eCQMs, we estimate 20 percent of HOPDs will voluntarily report one quarter of data for the measure in the CY 2027 reporting period, with 100 percent of HOPDs reporting the measure as required in subsequent years (86 FR 63962 and 63963, and 88 FR 82134)

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Studies have examined NNMT inhibition in relation to cellular methylation balance, NAD metabolism, and broader metabolic signaling pathways

In contrast to the proposed approach, many commenters indicated that the current MS-DRG cost-based methodology established in the FY 2007 IPPS rulemaking is a longstanding and better framework for improving the MS-DRG relative weights consistent with the statute

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