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Pathological mechanisms contributing to CIPN The pathological mechanisms underlying the development of CIPN have been studied extensively, and likely involve direct effects on the viability of sensory neurons, as well as cell-type specific consequences that occur downstream of on-target pharmacological activity of these cytotoxic drugs

It can be administered via infusion, intramuscular (IM), or intravenous (IV) injection

found that ASCT2 ligands chloroalanine, aminooxetane-3-carboxylate (AOC), and -FBP also inhibit ASCT2-mediated glutamine uptake in human melanoma cells [104]

MetALD was defined based on presence of steatotic liver disease and a history of both metabolic dysfunction and excessive alcohol use

Sylviane Tch and John Woodley for critical reading and English corrections of the manuscript

Then you send the sample to a mold testing company for analysis and receive back a moldiness score