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Cagrilintide, specifically as part of CagriSema, is further along in the regulatory process

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Tai PWL (2023) Integration of gene therapy vectors: a risk factor for tumorigenesis or another commensal property of adeno-associated viruses that benefits long-term transgene expression

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Overall, these studies suggest a possible efficacy of neuromodulation in determining a slight reduction of ALS progression, related to the type, duration and frequency of treatment, but current evidence remains preliminary (109, 110)