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It is also possible to increase the expression of neuroprotective factors in the body through gene therapy or drugs, such as Brain-Derived Neurotrophic Factor (BDNF) and Glial Cell Line-Derived Neurotrophic Factor (GDNF), thereby enhancing the survival ability of neuronal cells and extending the lifespan of ALS patients (56)

Moreover, lowering GSH levels by targeting the ser/gly synthesis pathway using sertraline may also increase the sensitivity of GBM cells to the redox-dependent effects of chloroquine

TLR2 and TLR4 expression patterns shift dramatically in obese AT, establishing these pattern recognition receptors as central inflammatory mediators

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6A) and a lower level of ATP (Fig

Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells