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Heavy metals are also known to interfere with the functioning of metalloproteins (proteins containing metal ions as cofactors) by modifying or replacing the essential divalent ions

However, the combination of MSG and TA demonstrated robust antioxidative effects, surpassing the outcomes of MSG treatment

The latter is the metabolic crossroads where the products of fatty acid beta oxidation and glucose metabolism through glycolysis can enter the tricarboxylic acid cycle (or Krebs cycle)

This downregulation contributed to increased apoptosis and elevated production of ROS (Ramakrishnan et al., 2016)

Farooq, Dry eye disease: An update in 2022

Blackwell, Oxford, pp 5366 Foyer CH, Halliwell B (1976) The presence of glutathione and glutathione reductase in chloroplasts: a proposed role in ascorbic acid metabolism