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Tumors were excised, weighed, and then used for serine content analysis

It reveals that altered glutathione and AA homeostasis induced by Trkb deletion in iSPNs is directly linked to early dopaminergic dysfunction and disrupted energy metabolism followed by age-dependent motor impairment and strongly supports the relevance of our model to elucidate the mechanisms underlying the vulnerability of iSPNs in neurodegenerative conditions

Testicular cancer, testicular trauma, testicular torsion (rotation of the testis, which can cut off blood flow), surgeries that affect testicular blood flow, and abnormal testicular development are some other testicular causes of infertility