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Aryal et al

The evolutionary history was inferred with MEGA X (Kumar et al, 2018), sequences were aligned using the MUSCLE algorithm, and a phylogeny was generated using the maximum likelihood method with the optimised Whelan and Goldman + Freq

One standout mechanism involves managing inflammation by guiding immune cells, specifically macrophages, from a pro-inflammatory state (M1 phenotype) to a pro-repair state (M2 phenotype)

Emerging evidence suggests that BL can abnormally activate TRPM2 channels, leading to pathological calcium influx and microglial overactivation

Wang J, Yan Z, Min H, Jiafan X, Kun C, Yi L et al

We used a 5-mL reaction solution in our experiments