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In murine MTB -challenge experiments, metE provided protection when administered as a recombinant protein formulated with either AS01 or AddaS03 adjuvants, with each formulation inducing distinct immune responses

Pushing past these limits does not accelerate results and may cause metabolic adaptation

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A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the bloodbrain barrier

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Instead, they prefer injections