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Description

CRC cells frequently remodel their TCA cycle due to mutations (KRAS, TP53), hypoxia, or dysregulated signaling, leading to intracellular accumulation and extracellular release of specific intermediatesincluding succinate, fumarate, itaconate, and -ketoglutarate (-KG)which function as potent immunometabolites by directly modulating immune cell metabolism, epigenetic programming, and signaling pathways ( Figure 3 )

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10.1111/j.2042-7158.2011.01366.x J

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By bolstering the body's intrinsic antioxidant defenses, L-theanine helps maintain the integrity of cellular membranes and supports overall metabolic health

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10.1016/j.carbpol.2021.118607 161 YangR.LiuX.RenY.XueW.LiuS.WangP.et al (2021b)

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THE IMMUNOLOGIC THEORY OF AGING

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W badaniu dotyczcym przecicia nerwu kulszowego u szczurw BPC-157 podawano po urazie w dawkach 10 g/kg lub 10 ng/kg

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