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Intended Use: This product is intended strictly for qualified laboratory researchers

In a journal article on plant-based vitamin B12 sources, researchers have claimed that purple larval and mushrooms are very healthy and rich sources of B12

Safety Toxicity No toxic or adverse effects have been associated with large intakes of vitamin B 12 from food or supplements in healthy people

A deficiency in one or more vitamins can lead to a wide variety of health problems, including fatigue, hair loss, and even death

Pharmacokinetics: Cyanocobalamin is administered intranasally, orally, and parenterally, while hydroxocobalamin is administered only parenterally. Once absorbed, vitamin B12 is highly bound to transcobalamin II, a specific B-globulin carrier protein and is distributed and stored primarily in the liver as coenzyme B12. The bone marrow also stores a significant amount of the absorbed vitamin B12. This vitamin crosses the placenta and is distributed into breast milk. Enterohepatic recirculation conserves systemic stores. The half-life is about 6 days (400 days in the liver). Elimination is primarily through the bile; however, excess cyanocobalamin is excreted unchanged in the urine

Upflow filters do not experience cementing of the bed, but they do not work if iron is present in the water