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Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments

& Morioka, T

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The significant changes in PI3K kinases (subunits) p85 and p110 and the absence of significant changes in PTEN suggested that the RRM2 regulation may activate Akt signaling through PI3K subunit stability regulation rather than the classical PTEN-dependent pathway