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Specifically, IRPs binding to IREs at the 5-UTR suppress translation of ferritin, FPN1, and amyloid precursor protein (APP), while IRP binding at the 3-UTR stabilizes mRNAs of TfR1 and DMT1, thereby promoting iron uptake under conditions of deficiency (Mai et al., 2023)

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Getting enough through either dietary sources or supplementation can help enhance weight loss, preserve muscle mass, improve exercise performance, boost mood and promote better sleep

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10.1016/j.toxrep.2014.09.016

Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons