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6972 IKK/NF-B facilitates autophagy induction by inducing the expression of an autophagy receptor, p62 (also called SQSTM1), mediating recruitment of damaged mitochondria for autophagic clearance via a ubiquitin-dependent mechanism

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Additionally, IL-6 acts not only as a pro-inflammatory mediator during this initial response but also helps modulate anti-inflammatory factors such as IL-10, maintaining immune homeostasis after exercise (79)