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Nat Neurosci 12:393395 Durieux PF, Schiffmann SN, de Kerchove dExaerde A (2012) Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions

Medicine has a long history of compounds that looked extraordinary in rodents, but failed or caused harm in people

The gut is not merely a digestive organit is a metabolic control center

Health status considerations: Generally healthy adults with physician clearance, individuals without contraindications (pregnancy, active malignancy, severe organ disease), those willing to commit to proper administration protocols and monitoring, and patients who understand the research-purposes-only status and informed consent requirements

The terminal carboxylic groups of PLGA chains impart its surface negatively charged, which can be modified through functionalization to facilitate targeted drug delivery 110

10.1186/s13011-015-0006-5 49 Shankara-NarayanaN.YuC.SavkovicS.DesaiR.FennellC.TurnerL.et al (2020)