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Direct causal links between specific Ca 2+ dynamics and macrophage fate outcomes, such as phagocytosis efficiency, intramacrophage bacterial killing, or apoptosis resistance, are largely absent in Klebsiella infection, with existing studies confined to mouse models and lacking human THP-1/PBMC validation, which is needed for clinical translation

Standard supplements (creatine, protein, vitamins, minerals) have no known interactions with therapeutic peptides