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This distinction fundamentally shapes its pharmacokinetic profile, granting it properties (oral bioavailability, protease resistance, BBB penetration) that most neuropeptides lack

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To assess the combined effects of different drugs, and measure potential drug synergy on cell proliferation, the method of Chou-Talay was used [25]

Plant Physiology 139, 806821

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doi: 10.1038/s41598-017-01822-0 143 WangSZhangKSongXHuangQLinSDengSet al