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Phase II Clinical Trials These promising preclinical findings led to Phase I and Phase II clinical trials in humans

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What did the clinical evaluation cover before the peptide was recommended

Kristoffer [Show all 7 contributors for this article] (2017)

In the absence of sufficient neurotrophic support, RGCs become more vulnerable to apoptotic signals triggered by excitotoxicity, amplifying neuronal damage and contributing to the progressive vision loss characteristic of glaucoma (111)

The glutathione addition onto electrophilic molecules is well-recognized and is mediated by specific classes of GSTs having usually a serine or a tyrosine as a catalytic residue