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2006 Oct;26(10):1225-33

Or it may look green if it was a B complex vitamin supplement, adds Cleveland Clinic

B12 is generally safe, but certain medicationssuch as metformin, proton pump inhibitors, or some antibioticscan impact B12 absorption or effectiveness

Hence, cobalamin-related remethylation disorders are usually treated by intramuscular (IM) injections at an individually titrated, minimum effective dose