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Beyond T-cell modulation, macrophages (Ms) exhibit remarkable plasticity, differentiating into pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to microenvironmental cues

Morse MA, Lu J, Gopalakrishnan R, Peterson LA, D'Ambrosio SM, Wani G, et al

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Furthermore, GltT-defective mutants, but not GltS-defective mutants, showed slightly reduced survival in HeLa cells (Monaco et al., 2006), and were significantly attenuated in a murine model of meningococcal meningitis (Colicchio et al., 2009) and in systemic murine models of infection (Li et al., 2009

Kunkel TA, Erie DA

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