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Research Applications: Tissue Repair and Cellular Regeneration BPC-157 (Body Protection Compound-157) has been studied extensively in preclinical settings for its role in tissue repair and angiogenesis

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A follow-up study is in progress, and Relyvrio's manufacturer, Amylyx Pharmaceuticals, has pledged to withdraw the medication if the trial fails to demonstrate efficacy

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Mechanistically, neuronal death protection from autophagy seems to involve the MET downstream mTOR signaling, whose activation (phosphorylation) is enhanced after tMCAO (Shang et al., 2010)