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The most common side effects in people with metastatic colorectal carcinoma who take XELODA alone include: decreased red blood cell count diarrhea nausea hand and foot syndrome tiredness increased bilirubin level in your blood stomach-area (abdominal) pain The most common side effects in people with metastatic breast cancer who take XELODA in combination with docetaxel include: diarrhea hair loss swelling mouth sores or mouth inflammation hand and foot syndrome stomach-area (abdominal) pain nausea and vomiting The most common side effects in people with metastatic breast cancer who take XELODA alone include: decreased white blood cell and red blood cell count nausea and vomiting diarrhea tiredness hand and foot syndrome skin inflammation, including rash Severe allergic reactions can happen with XELODA

This drug can cause fetal harm, but potential benefits may warrant use of this drug in some pregnant women

A 2025 systematic review identified 36 studies from 1993 to 2024, including 35 preclinical studies and only 1 clinical study

This study was the only one that reported any significant cytotoxic effects of a PPI

[link] Sereti, K.I., Nguyen, N.B., Kamran, P., Zhao, P., Ranjbarvaziri, S., Park, S., Sabri, S., Engel, J.L., Sung, K., Kulkarni, R.P., Ding, Y., Hsiai, T.K., Plath, K., Ernst, J., Sahoo, D., Mikkola, H.K.A., Iruela-Arispe, M.L., and Ardehali, R., "Analysis of cardiomyocyte clonal expansion during mouse heart development and injury", Nature Communications 9 (1): 1-13 (2018)

a similar effect was also observed in alfalfa treated with trivalent chromium (Barton et al., 1 chromium treatments can greatly inhibit convolvulus stem, elongation did not affect leaf biomass accumulation (Gardea-Torresdey et al., It is generally believed that the presence of chromium affects plant photosynthesis and disrupts plant growth