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According to the RNA-seq results from CCl 4 -induced ALI models, GSEA analysis showed the pathway-related to cell-cell adhesion, cell substrate adhesion, cell substrate junction and cell-cell recognition were significantly enriched, indicating that pyroptotic hepatocyte may further communicated with other types of liver cells in ALI (Figure S5A)

Hence, targeting oxidative stress in IBD diagnosis emerges as a promising avenue with far-reaching implications

10.1038/s41385-021-00383-w 21 DavisM

Zinc and copper are also important cofactors in collagen formation

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Ulcerative colitis causes inflammation and sores (ulcers)