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DOI 10.1242/dev.126.21.4653

Papazian, "Spinocerebellar ataxia type 13 mutation associated with disease onset in innfancy disrupts axonal pathfinding during neuronal development", Disease Models and Mechanisms 5: 921-929 (2012)

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These shifts compromise intestinal barrier integrity, promote metabolic endotoxemia, and activate toll-like receptor-driven oxidative and inflammatory cascades that propagate IR and HA

Vitamin D regulates pancreatic beta cell function both directly as well as indirectly by modulating extracellular calcium and the flow of calcium through beta cells