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Konzo is characterized by a sudden onset of a non-progressive spastic paraparesis of varying severity, evolving as a mild (stage 1), moderate (stage 2), or severe (stage 3) form of neurodisability 1

Ferroptosis-associated patterns linked with the tumor microenvironment diversity and immune response phenotype have been identified (80)

Unfortunately, such vitamin B12 injection dosage and frequency advice is common

Despite these promising clinical data, JAKinibs should be used with caution because of their side effects, based on the following considerations: (1) nonselective inhibition of the JAK/STAT pathway increases the risk of secondary infection such as herpes zoster virus reactivation given its general inhibitory effects on multiple aspects of physiological actions, including the innate immune system

There were no differences in the extent of subchondral bone remodeling between the genotypes (Supplementary Fig

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