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Myofibroblasts regulate not only the deposition of ECM but also the EMT process, thereby driving tissue fibrosis

After 2 week acute toxicity and cumulative tests in mice, no statistical difference existed between LAAM GSH-CQD group and normal control group in the parameters from complete blood count and serum biochemistry analyses (Supplementary Fig

Control, p .05, Table 1)

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Recently, meta-analysis of GWAS in 30,118 individuals of European ancestry showed four significant loci associated with circulating glycine levels [121]: two loci at the glycine cleavage system (GCS) subunits, protein P (SNP rs71503800 at GLDC , glycine decarboxylase) and protein H (SNP rs11860711 at GCSH )

doi: 10.1186/1471-2202-7-29 36