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It can be a serious problem and will need a GP to diagnose and recommend treatment

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Symptoms of a severe allergic reaction can include: swelling under your skin, typically in your eyelids, lips, hands, or feet swelling of your tongue, mouth, or throat trouble breathing low blood pressure Symptoms of serious allergic reaction, such as decreased blood pressure and trouble breathing, have been reported in people taking Prolia

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As a foreign protein, arginine deiminase may induce antibody induction and anaphylaxis, causing undesired adverse effect and shortened half-life of the drug [131]