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Wang Y, An H, Liu T, Qin C, Sesaki H, Guo S, Radovick S, Hussain M, Maheshwari A, Wondisford FE, et al

Subsequent trials must emphasize phase III research for lycopene, GT polyphenols (EGCG), concentrating on endpoints like PSA kinetics, PSADT, NF-B activity, and tissue biomarkers (eg, Ki-67, 8-OHdG)

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Vit-B12 is also an essential nutrient for skeletomusculargutbrain axis to maintain skeletal muscle, neuro-cognitive functions, and modulate gut microbiota 550,551