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doi: 10.1093/toxsci/kfu113

Umanath K, Lewis JB

Nature 2012;489:22030

Vijayavel K, Balasubramanian MP (2008) DNA damage and cell necrosis induced by naphthalene due to the modulation of biotransformation enzymes in an estuarine crab Scylla serrata

For example, after systemic administration of GH for 14 days, human data have reported an increase in circulating IGF-1 and expression of IGF-1 in tendon tissue, accompanied by increased expression of tendon collagen in individuals ( in vivo studies, which have demonstrated that local administration of IGF-1 (1 mg) directly induced an elevation in collagen synthesis in human tendon tissue ( The above findings combined to demonstrate that IGF-1 is sufficient to increase collagen production in tenocytes