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Among these, coumarin and L-leucine showed the highest test statistics and lowest p-values, indicating stronger group separation relative to other metabolites, while L-octanoylcarnitine and kaempferol exhibited more moderate but consistent differences

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As the main transcription factor of Th17 cell, RORt collaborates with other transcription factors, such as ROR, IRF4, and Runx1, to synergistically stimulate Th17 cell growth and IL-17 release ( Foxp3 interacts with several transcription factors, such as STAT5, NFAT, and BACH2, to influence the Treg cells' development, stability, and epigenetic modifications

Results A total of 4, 241 female participants from four NHANES cycles were included in this study

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cerevisiae for winemaking: fermentation-related trait diversity in the genus Saccharomyces