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Freezing causes ice crystal formation, which physically disrupts the molecular structure of B12 and lipotropic compounds
My understanding is that this should be done routinely, especially if you're on B12 in high doses, but most GP's don't know this and don't do it
2017 Jun;6(6):2222-2225 Kulshreshtha B, Pahuja I, Kothari D, Chawla I, Sharma N, Gupta S, Mittal A
When choosing between B12 and MIC B12 injections, it's important to consider individual health goals and whether the additional lipotropic compounds align with specific need
Confirmed Vitamin B12 Deficiency: Patients with a confirmed diagnosis of vitamin B12 deficiency