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This mechanism provides a clear, molecular explanation for why many Long COVID patients report a significant lifting of their brain fog and an improvement in mental clarity after initiating a high-quality methylcobalamin protocol

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Metabolic activity was determined using a WST1 assay (Cayman) according to the manufactures protocol, after exposure to increasing concentrations of cuprizone (0250 M) for up to 72 h, or 20 M peroxide as positive control