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Primary Cellular Pathways FAK/Paxillin Signaling Cell Migration and Adhesion BPC-157 significantly increases phosphorylation of focal adhesion kinase (FAK) and paxillin proteins in fibroblast cells, promoting enhanced cell adhesion and migration[1]

A 2025 systematic review published in the Orthopaedic Journal of Sports Medicine examined 36 studies on BPC-157 published between 1993 and 2024

Studies on mice lacking annexin A2 showed normal fat tissue vascularization and adipogenesis but reduced fatty acid uptake, resulting in smaller fat deposits