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Researchers must also generate non-clinical evidence demonstrating that the compound interacts with the intended target and produces the expected pharmacological effects without showing major safety concerns

Journal of Nutrition and Biochemistry, 42(2), 219-228

In AD, intramuscular DFO significantly slowed the rate of dementia progression and decline in daily living skills (P = 0.028), despite its limited CNS penetration and an unclear mechanism (Crapper McLachlan et al., 1991)

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