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Both methods have been used to transform [13C6]aniline into folic acid, labelled with [13C6] in the p-aminobenzoate moiety, and [3,3,4,4-2H4]-L-glutamic acid into folic acid, labelled with [2H4] in the glutamate moiety

Funding This study was supported by the National Natural Science Foundation of China (82104534, 81903902) and the Sichuan Province Science Research Special Funding Project for Postdoctoral Fellows (2022BSH044)

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated mA-demethylation of NANOG mRNA

Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

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Hexosamine biosynthetic pathway The hexosamine biosynthetic pathway (HBP) is an alternative secondary route within glucose metabolism that processes fructose-6-phosphate (F6P) and glutamine into glucosamine-6-phosphate (G6P) through the enzymatic action of glutaminefructose-6-phosphate transaminase (GFPT), present in the forms of GFPT1 and GFPT2, with GFPT2 being the primary isoform active in cardiac tissue [90]