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After protein enclosure and autophagosome completion, lysosomes interact with this structure to degrade the autophagosome contents, a process mediated by SNARE complexes, which facilitate membrane fusion (Sllner et al., 1993

Acknowledgements The work was carried out within the Program for Fundamental Research of the N.S

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When administered under medical supervision, glutathione injections are generally well tolerated by most individuals

Similar content being viewed by others Introduction Targeted protein degradation (TPD) involves co-opting the cellular protein degradation machinery to degrade disease-causing proteins

Changes in hypothalamic agouti-related protein (AGRP), but not alpha-MSH or pro-opiomelanocortin concentrations in dietary-obese and food-restricted rats