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doi: 10.1111/j.1600-079X.2008.00555.x 73 SatiL

Wan, H., Sun, D

Cells were lysed at 4 C in a radioimmunoprecipitation assay (RIPA) lysis buffer (Beyotime Biotechnology)

7 Chronotherapy and aging Pharmacotherapy, traditionally based on standardized dosing protocols, presents considerable challenges when applied to the geriatric population

Measurements of the intracellular accumulation of the HMCD-drug conjugates, in addition to the metabolite profile within tumor cells, will determine whether the increase in potency is related to an increase in the concentration of the drug within the cell, or if the activity is attributed to the formation of a more toxic metabolite

The reaction was centrifuged at 4,000 rpm for 10 min