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*Correspondence: Wufei Zhu, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, mortality rate was significantly higher in patients with CDI within 1 year of transplant compared to those without CDI (26.7% vs 12.8%, p =0.031)

Therefore, the first amide bond between (2 S ,3 S )- t -ES and l-Ile is catalyzed by Cp1B, while formation of the second amide bond between 14 and putrescine is catalyzed by Cp1D (Fig

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1, Figure S1 and Supplementary data S1): the glutathione pathway, which encompasses the intake of cystine, production of glutathione (GSH) and GSH usage by glutathione peroxidase 4 (GPX4) to reduce lipid peroxides 22