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However, we did not detect any changes in the transcription of glt-1 after treatment with BSO (data not shown), suggesting that xct upregulation could lead to increased extracellular glutamate levels, as observed in mice that have been gestationally exposed to arsenic (Ramos-Chvez et al., 2015

Chyra-JachDKaletkaZDobrakowskiMMacho-GreckaAKasperczykSBellantiFet al

[DOI] [PubMed] [Google Scholar] 265

All four datasets were available to the public and compared the gene expression between cell types, stages of disease progression and gender

It has been reported that across Europe 35% of adolescents of the general population presented folate insufficiency and 15% deficiency while only 2% had low vitamin B 12 levels [35, 36], though this contrasts with a previous review of European studies which found no folate or B 12 deficiencies in blood levels, but did not report data regarding insufficiencies [37]

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