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In summary, after consideration of the public comments we received, input from our Medical Officers, and the HOP Panel recommendation, we are finalizing the APC and status indicators for CPT codes 92930 and 92945 with modification

Therefore, exposure to foreign antigens from the first stimulus or to EBV viral antigens leads to activation of CD4 T cells and IFN- release, provided that the cells presenting these antigens to CD4 T cells are not previously infected with EBV, since the gp42HLA-II complex in these cells would prevent their activation [171, 194]