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[0175] Embodiment 168: The formulation according to any one of embodiments 166-167, wherein said formulation is formulated for administration via a route selected from the group consisting of oral administration, nasal administration, rectal administration, intraperitoneal injection, intravascular injection, subcutaneous injection, transcutaneous administration, and intramuscular injection

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Additionally, in the skin of NRF2-deficient psoriasis-like mice, the STAT3 and NF-B pathways were activated, and K16 expression increased (Fig

The downside of MSC clinical applications is their heterogeneity which is dependent on the source of their procurement and the donor-to-donor variability [115, 116]

Retrieved August 12, 2022 from Acknowledgements We thank Chris James and Philip Wong for their oversight of the bioanalytical methods, Manpreet Virk and Valerie Kramlinger for carrying out select in vitro phenotyping experiments, Brooke Rock for guiding the proteomics experiments and supporting data analysis troubleshooting, and Marintan Spring and Shauna Hutton for their support in the preparation of this manuscript and contributions to the PK analysis and clinical study report during the conduct of the study, respectively