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PXR, Pregnane X receptor

When heptanoate is metabolized by -oxidation, it generates two molecules of acetyl-CoA and one molecule of propionyl-CoA

It increased the relative abundance of Bacteroides while reducing Escherichia and Shigella spp., alongside upregulating occludin and downregulating claudin-2

Apoptosis in sepsis LLPS is involved in the stability of the p53-mediated transcriptional initiation of apoptosis [97]

Antioxidants 13(2):182 Mishima E et al (2020) Drugs repurposed as antiferroptosis agents suppress organ damage, including AKI, by functioning as lipid peroxyl radical scavengers