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Hepatic GSH levels are greatly affected by diet and fasting alone severely depletes hepatic GSH stores in as little as 6 hrs [34]

Cross-comparison of cytoskeleton-related proteins regulated by curcumin (Table 2) with the overlapping proteins affected by both curcumin and Taxol (Table 1) highlighted CLASP2 as a common regulatory target (Figure 3D)

It is not a substitute for controlled single-compound work, but it can be relevant for exploratory combination-protocol designs where the research question is broader tissue remodeling rather than isolating one pathway

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