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In line with these observations, we found halved concentration of hepatic GSH in APAP-treated LivPGC-1 mice compared to control ones (Fig

The content of total polysaccharides decreased significantly in S1S3, decreased slowly in S4S7, compared to the S0, the content of polysaccharides in S9 decreased by 47.38%

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Since several studies point to an involvement of oxidative stress in the development of DPN, the antioxidative potential of B 12 suggests that B 12 administration may be justified, not only for the therapy of overt DPN, but also in early stages of DPN, or even for prevention of DPN when cellular oxidative stress is present but symptoms are mostly absent

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An older The study included 756 participants