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Formic acid, acetonitrile, and water were purchased from Fisher Scientific (Fair Lawn, NJ, USA)

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Glutathione IV therapy is known to produce particularly successful results in treating patients who are recovering from conditions such as strokes, or those who are afflicted with hepatitis, neurodegenerative disorders such as Parkinsons disease, and other chronic illnesses

Both NOX and inducible nitric oxide synthase (iNOS) are vital in generating enhanced ROS levels within phagocytes via oxidative burst to kill invading pathogens ( 2 - produced by NOX is dismutated into H 2 O 2 by superoxide dismutase1 (SOD1), whereas nitric oxide produced by inducible nitric oxide synthase (iNOS) reacts with O 2 - resulting in peroxynitrite production ( Mitochondria are considered as the redox-active compartment within the cell, accounting for nearly 90% of oxygen utilization ( 2 -

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These drugs include molecules already approved for human use, such as statins and niacin, and particularly, compounds currently undergoing development such as apolipoprotein A-I mimetics and reconstituted HDL preparations