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Discovery of Selective, Substrate-Competitive, and Passive Membrane Permeable Glycogen Synthase Kinase-3beta Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling of New C-Glycosylflavones

PMID 6301011

INDICATIONS : Glutathione is used in liver disease

67 mM Potassium Phosphate Buffer, pH 6.8 at 37C (Prepare 100 ml in deionized water using Potassium Phosphate, Monobasic, Anhydrous, Sigma Prod

Possible side effects or risks may include: Injection site pain, redness, or irritation Headache Nausea Fatigue Dizziness Fluid retention Changes in appetite Immune or allergic reactions Unwanted tissue effects Infection risk from improper injection technique Unknown long-term risks Because the long-term safety data for many emerging peptides remains limited, patients should be cautious about anyone promising guaranteed results or claiming that peptide therapy is risk-free

Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies