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On the one hand, excessive ROS generation is involved in the process of chondrocyte growth inhibition and apoptosis promotion through signaling pathways, such as PI3K/AKT and p38 pathways (238, 239)

The process of acetylation shields the thiol group from oxidation prior to absorption, ensuring that once inside the cell, S-Acetyl-L-glutathione is hydrolyzed by cytoplasmic thioesterases, thereby replenishing the intracellular GSH pool

The species-specific constants can be obtained as the product of total species concentration and the relative abundance of the respective microspecies

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Interleukin-22 ameliorates neutrophil-driven nonalcoholic steatohepatitis through multiple targets